Tiagabine
Tiagabine
Tiagabine (pronounced tee-ah-gah-been) is a medication used in the treatment of epilepsy. It is an anti-epileptic drug (AED), also known as an anticonvulsant.
Etymology
The name "Tiagabine" is derived from its chemical structure, which is a nipecotic acid derivative. The "Tia" part of the name is an abbreviation of "thiazine", a part of its chemical structure, and "gabine" is a reference to its action on the GABA (gamma-aminobutyric acid) neurotransmitter system.
Usage
Tiagabine is used to control partial seizures (a type of epilepsy) in adults and children aged 12 years and older. It works by slowing down impulses in the brain that cause seizures. Tiagabine is used in combination with other seizure medications.
Mechanism of Action
Tiagabine works by inhibiting the reuptake of the neurotransmitter GABA, thereby increasing the concentration of GABA in the brain. GABA is the main inhibitory neurotransmitter in the brain, and increasing its levels can help to calm neuronal activity and prevent seizures.
Side Effects
Common side effects of Tiagabine include dizziness, tiredness, nausea, and difficulty concentrating. More serious side effects can include mood changes, hallucinations, and severe rash.
Related Terms
See Also
External links
- Medical encyclopedia article on Tiagabine
- Wikipedia's article - Tiagabine
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