14-Methoxymetopon
14-Methoxymetopon
14-Methoxymetopon (pronunciation: 14-meth-oxy-met-o-pon) is a potent opioid analgesic drug that is derived from opium. The etymology of the term is derived from the Greek words "methoxy" which means "with oxygen" and "metopon" which means "forehead", referring to the location where the drug is often applied.
Description
14-Methoxymetopon is a semi-synthetic opioid that is structurally related to morphine. It is a potent analgesic that is approximately 500-1000 times more potent than morphine in animal models. It is used in the treatment of severe pain, such as that experienced by patients with advanced cancer.
Pharmacology
14-Methoxymetopon acts primarily on the mu-opioid receptor, which is responsible for the drug's analgesic effects. It also has a high affinity for the kappa-opioid receptor, which may contribute to its analgesic potency.
Side Effects
Like other opioids, 14-Methoxymetopon can cause a range of side effects, including nausea, vomiting, constipation, and respiratory depression. It also has a high potential for addiction and dependence.
Related Terms
- Opioid
- Morphine
- Mu-opioid receptor
- Kappa-opioid receptor
- Cancer
- Nausea
- Vomiting
- Constipation
- Respiratory depression
- Addiction
- Dependence
External links
- Medical encyclopedia article on 14-Methoxymetopon
- Wikipedia's article - 14-Methoxymetopon
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