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What is 14-Methoxymetopon?

  • It is a highly potent analgesic drug that is around 500 times stronger than morphine when administered systemically.
  • IUPAC Name: (4R,4aS,7aR,12bR)-9-hydroxy-4a-methoxy-3,7a-dimethyl-1,2,4,5,6,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
  • InChI: InChI=1S/C19H23NO4/c1-17-14(22)6-7-19(23-3)13-10-11-4-5-12(21)16(24-17)15(11)18(17,19)8-9-20(13)2/h4-5,13,21H,6-10H2,1-3H3/t13-,17+,18+,19-/m1/s1
  • Canonical SMILES: CC12C(=O)CCC3(C14CCN(C3CC5=C4C(=C(C=C5)O)O2)C)OC
  • Isomeric SMILES: C[C@]12C(=O)CC[C@@]3([C@]14CCN([C@@H]3CC5=C4C(=C(C=C5)O)O2)C)OC
  • Molecular formula: C19H23NO4
  • Molecular weight: 329.4 g·mol−1
  • Synonyms:
  1. 131575-03-6
  2. CHEMBL326684
  3. Morphinan-6-one, 4,5-epoxy-3-hydroxy-14-methoxy-5,17-dimethyl-, (5alpha)-
  4. SCHEMBL1231312
  5. DTXSID50927273
  6. BDBM50142700
  7. PDSP2_001435
  8. Q4549584
  9. 3-Hydroxy-14-methoxy-5,17-dimethyl-4,5-epoxymorphinan-6-one



  1. National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 5486940, 14-Methoxymetopon. Retrieved August 3, 2021 from [1].

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