Alvimopan
Alvimopan (pronunciation: al-vi-mo-pan) is a peripherally acting mu-opioid receptor antagonist (PAMORA) used to accelerate the time to upper and lower gastrointestinal recovery following surgeries that include partial bowel resection with primary anastomosis.
Etymology
The term "Alvimopan" is derived from its chemical structure. It is a synthetic derivative of naltrexone, a opioid antagonist. The prefix "Alvi-" is derived from the Latin word "alvus" meaning belly, and "mopan" is an arbitrary suffix.
Pharmacology
Alvimopan competitively binds to mu-opioid receptors in the gastrointestinal tract and blocks the inhibitory effects of opioid medications on the gastrointestinal tract. This action accelerates the time to gastrointestinal recovery, which can be delayed by opioid medications.
Clinical Use
Alvimopan is used in the hospital setting to accelerate the time to gastrointestinal recovery following surgeries that include partial bowel resection with primary anastomosis. It is not intended for long-term use.
Related Terms
- Peripherally acting mu-opioid receptor antagonists (PAMORAs)
- Gastrointestinal tract
- Opioid
- Mu-opioid receptors
- Bowel resection
- Naltrexone
See Also
External links
- Medical encyclopedia article on Alvimopan
- Wikipedia's article - Alvimopan
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski