Diphenoxylate
Diphenoxylate (pronunciation: dye-fen-OX-i-late) is a medication primarily used to treat diarrhea. It is a narcotic that slows down the movement of the intestines, allowing the body to absorb more fluid and reducing the frequency of bowel movements.
Etymology
The term "Diphenoxylate" is derived from its chemical structure, which includes two phenyl groups (diphenyl) and an oxylate group.
Pharmacology
Diphenoxylate works by slowing down the movement of the intestines. This decrease in motility allows the intestines to absorb more water and electrolytes, reducing the frequency and volume of bowel movements. It is often combined with atropine to discourage misuse.
Usage
Diphenoxylate is used in the treatment of diarrhea that has not responded to non-drug treatments. It is typically used in combination with atropine (as in the brand name Lomotil) to prevent misuse.
Side Effects
Common side effects of diphenoxylate include drowsiness, dizziness, and dry mouth. More serious side effects can occur, including severe stomach pain or bloating, ongoing or worsening diarrhea, or signs of dehydration.
Related Terms
See Also
External links
- Medical encyclopedia article on Diphenoxylate
- Wikipedia's article - Diphenoxylate
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