Phenomorphan
Phenomorphan
Phenomorphan (pronounced: /ˌfiːnoʊˈmɔːrfən/) is a potent opioid analgesic drug that is not currently used in medicine. It is a derivative of morphine, being the 3-phenyl derivative of levorphanol.
Etymology
The term "Phenomorphan" is derived from the words "phenyl", referring to the phenyl group present in its chemical structure, and "morphine", the opioid from which it is derived.
Pharmacology
Phenomorphan acts as an agonist at the mu-opioid receptor, the main therapeutic target for most opioid analgesics. It is more potent than morphine but less potent than levorphanol.
Related Terms
- Opioid: A class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine, and many others.
- Morphine: A pain medication of the opiate family which is found naturally in a number of plants and animals.
- Levorphanol: A synthetic opioid medication used to treat severe pain.
- Agonist: A chemical that binds to a receptor and activates the receptor to produce a biological response.
- Mu-opioid receptor: A class of opioid receptors with high affinity for enkephalins and beta-endorphin but low affinity for dynorphins.
External links
- Medical encyclopedia article on Phenomorphan
- Wikipedia's article - Phenomorphan
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