Zanoterone
Zanoterone
Zanoterone (pronounced: zah-noh-tehr-ohn) is a steroidal antiandrogen that was never marketed. It is a synthetic and steroidal compound that acts as a competitive antagonist of the androgen receptor (AR).
Etymology
The term "Zanoterone" is derived from the scientific nomenclature of its chemical structure. The prefix "Zano-" is a modification of "Azano-", referring to the presence of nitrogen in the compound's structure. The suffix "-terone" is commonly used in the naming of steroidal compounds, indicating its classification as a steroid.
Usage
Zanoterone was developed for potential use in the treatment of prostate cancer and benign prostatic hyperplasia, but development was discontinued due to the occurrence of adrenal insufficiency as a side effect in some patients.
Related Terms
- Androgen receptor: A type of nuclear receptor that is activated by binding any of the androgenic hormones, usually testosterone or dihydrotestosterone.
- Steroidal antiandrogen: A type of antiandrogen — the name given to any of the antagonist of the androgen receptor.
- Prostate cancer: A form of cancer that develops in the prostate, a gland in the male reproductive system.
- Benign prostatic hyperplasia: An increase in size of the prostate in middle-aged and elderly men.
- Adrenal insufficiency: A condition in which the adrenal glands do not produce adequate amounts of steroid hormones.
External links
- Medical encyclopedia article on Zanoterone
- Wikipedia's article - Zanoterone
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