Paliperidone palmitate
Paliperidone Palmitate
Paliperidone palmitate (/pælɪˈpɛrɪdoʊn pælˈmɪteɪt/) is a long-acting injectable antipsychotic used for the treatment of schizophrenia and schizoaffective disorder. It is a palmitate ester of paliperidone, a metabolite of risperidone, and is administered via intramuscular injection.
Etymology
The name "paliperidone" is derived from the parent drug, risperidone, and the suffix "-palmitate" refers to the palmitic acid ester group attached to the molecule, which allows for its long-acting properties.
Pharmacology
Paliperidone palmitate is a dopamine antagonist, specifically a D2 antagonist, which works by blocking dopamine receptors in the brain. It also has effects on serotonin, norepinephrine, and histamine receptors.
Usage
Paliperidone palmitate is used primarily in the treatment of schizophrenia and schizoaffective disorder. It may also be used in the treatment of other conditions as determined by a healthcare provider.
Side Effects
Common side effects of paliperidone palmitate include insomnia, anxiety, weight gain, and extrapyramidal symptoms. Serious side effects may include neuroleptic malignant syndrome, tardive dyskinesia, and orthostatic hypotension.
See Also
External links
- Medical encyclopedia article on Paliperidone palmitate
- Wikipedia's article - Paliperidone palmitate
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