Clomipramine

Clomipramine

Clomipramine (pronounced klo-MIP-ra-meen) is a tricyclic antidepressant (TCA) used in the treatment of obsessive-compulsive disorder (OCD). It is sold under the brand name Anafranil among others.

Etymology

The term "Clomipramine" is derived from its chemical structure, which is a chlorinated derivative of imipramine.

Usage

Clomipramine is primarily used to treat obsessive-compulsive disorder (OCD). It is also used in the treatment of major depressive disorder, panic disorder, and various types of pain.

Mechanism of Action

Clomipramine works by increasing the levels of serotonin and norepinephrine in the brain, which helps to elevate mood and relieve symptoms of OCD.

Side Effects

Common side effects of Clomipramine include dry mouth, constipation, loss of appetite, weight gain, sleepiness, and sexual dysfunction. In rare cases, it can cause more serious side effects such as suicidal thoughts, mania, and serotonin syndrome.

Related Terms

• Tricyclic antidepressant (TCA)
• Obsessive-compulsive disorder (OCD)
• Serotonin
• Norepinephrine
• Major depressive disorder
• Panic disorder
• Pain
• Sexual dysfunction
• Suicidal thoughts
• Mania
• Serotonin syndrome

External links

• Medical encyclopedia article on Clomipramine
• Wikipedia's article - Clomipramine

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